Recombinant Human Serpin A8 (C-6His)

Description

EnkiLife provides the Recombinant Human Serpin A8 (C-6His) protein,aslo know as Angiotensinogen,Serpin A8,AGT and SERPINA8, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Serine Protease Inhibitor-clade A8 is produced by our Mammalian expression system and the target gene encoding Asp34-Ala485 is expressed with a 6His tag at the C-terminus.Accession:AAH11519.1. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:50.8 KDa. Background:Angiotensinogen is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Genetic variations in Angiotensinogen are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in the encoding gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.