Recombinant Human Serpin B3 (C-6His)

Description

EnkiLife provides the Recombinant Human Serpin B3 (C-6His) protein,aslo know as Serpin B3,Protein T4-A,Squamous cell carcinoma antigen 1,SCCA-1;serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3,serpin peptidase inhibitor, clade B (ovalbumin), member 3,Squamous cell carcinoma antigen 1,T4-A;SCCA1, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Serine Protease Inhibitor-clade B3 is produced by our Mammalian expression system and the target gene encoding Met1-Pro390 is expressed with a 6His tag at the C-terminus.Accession:P29508. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:45.96 KDa. Background:Serpin B3, also known as squamous cell carcinoma antigen-1 (SCCA-1), is a member of the serpin superfamily of serine protease inhibitors. Serpin B3 belongs to the subgroup ovalbumin-related serpins which are involved in the regulation of apoptosis, inflammation, angiogenesis and embryogenesis. It may act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. It also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1).