Recombinant Human Serpin H1 (C-6His)

Description

EnkiLife provides the Recombinant Human Serpin H1 (C-6His) protein,aslo know as Serpin H1,47 kDa Heat Shock Protein,Arsenic-Transactivated Protein 3,AsTP3,Cell Proliferation-Inducing Gene 14 Protein,Collagen-Binding Protein,Colligin,Rheumatoid Arthritis-Related Antigen RA-A47,SERPINH1,CBP1,CBP2,HSP47,SERPINH2, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Serine Protease Inhibitor-clade H1 is produced by our Mammalian expression system and the target gene encoding Ala19-Leu418 is expressed with a 6His tag at the C-terminus.Accession:P50454. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:45.5 KDa. Background:Serpin H1 is a serine proteinase inhibitors Which belongs to the serpin family. Serpin H1 is induced by heat shock. Serpin H1 localizes to the endoplasmic reticulum lumen and binds specifically to collagen. Thus it is thought to be a molecular chaperone involved in the maturation of collagen molecules. Autoantibodies to this protein have been found in patients with rheumatoid arthritis. Serpin H1 may be a marker for cancer and nucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm premature rupture of membranes.