Recombinant Human SGSH (C-6His)

Description

EnkiLife provides the Recombinant Human SGSH (C-6His) protein,aslo know as N-Sulphoglucosamine Sulphohydrolase,Sulfoglucosamine Sulfamidase,Sulphamidase,SGSH,HSS, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human N-Sulphoglucosamine Sulphohydrolase is produced by our Mammalian expression system and the target gene encoding Arg21-Leu502 is expressed with a 6His tag at the C-terminus.Accession:P51688. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:55.72 KDa. Background:N-Sulphoglucosamine Sulphohydrolase (SGSH) is an important member of the sulfatase family which is involved in the degradation of heparin sulfate. SGSH binds one calcium ion per subunit as a cofactor. SGSH catalyzes N-sulfo-D-glucosamine and H2O to D-glucosamine and sulfate. SGSH deficiency is result in mucopolysaccharidosis type 3A (MPS3A), a recessive lysosomal storage disease characterized by neurological dysfunction but relatively mild somatic manifestations.