Recombinant Human SGTA (N-6His)

Description

EnkiLife provides the Recombinant Human SGTA (N-6His) protein,aslo know as Small Glutamine-Rich Tetratricopeptide Repeat-Containing Protein Alpha,Alpha-SGT,Vpu-Binding Protein,UBP,SGTA,SGT,SGT1, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Small Glutamine-Rich Tetratricopeptide Repeat-Containing Protein Alpha is produced by our E.coli expression system and the target gene encoding Met1-Glu313 is expressed with a 6His tag at the N-terminus.Accession:O43765. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:36.2 KDa. Background:Small Glutamine-Rich Tetratricopeptide Repeat-Containing Protein α (SGTA) is an ubiquitously expressed protein which belongs to the SGT Family. SGTA contains three TPR Protein-Protein Interaction Duplicates. SGTA is a co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity. SGTA is capable of interacting with the major nonstructural protein of Parvovirus H-1 and 70-kDa heat shock cognate protein. It interacts with NS1 from Parvovirus H-1, with Vpu and Gag from HIV-1. It also interacts with SARS-CoV Accessory Protein 7a, DNAJC5 and DNAJC5B. However, its function is not known. Since this transcript is expressed ubiquitously in various tissues, SGTA may serve a housekeeping function.