Recombinant Human Siglec-6 (C-Fc)

Description

EnkiLife provides the Recombinant Human Siglec-6 (C-Fc) protein,aslo know as CD327,CD33 antigen-like 1,CD33L1,CDw327,OB-BP1,Siglec6,Siglec-6, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Sialic acid-binding Ig-like lectin 6 is produced by our Mammalian expression system and the target gene encoding Glu27-Val331 is expressed with a human IgG1 Fc tag at the C-terminus.Accession:O43699-3. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:60.6 KDa. Background:Siglec-6, also known as CD327, belongs to the immunoglobulin superfamily, SIGLEC (sialic acid binding Ig-like lectin) family. Siglec-6 mediates sialic-acid dependent binding to cells. Siglec-6 binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. Siglec-6 may show increasing expression human labor and following childbirth, it has been speculated that this expression helps to slow the tempo of human labor. Siglec-6 is found on B cells and in placenta, and would seem to have a restricted specificity for the sialyl Tn antigen.