Recombinant Human SIRPG (C-Fc)

Description

EnkiLife provides the Recombinant Human SIRPG (C-Fc) protein,aslo know as Signal-Regulatory Protein Gamma,SIRP-Gamma,CD172 Antigen-Like Family Member B,Signal-Fegulatory Protein Beta-2,SIRP-b2,SIRP-Beta-2,CD172g,SIRPG,SIRPB2, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Signal-Regulatory Protein Gamma is produced by our Mammalian expression system and the target gene encoding Glu29-Pro360 is expressed with a human IgG1 Fc tag at the C-terminus.Accession:Q9P1W8. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:63.9 KDa. Background:Signal-Regulatory Protein Gamma (SIRPG) is a member of the signal-regulatory protein (SIRP) family and also belongs to the immunoglobulin superfamily. SIRPG is detected in the liver, and at very low levels in the brain, heart, lung, pancreas, kidney, placenta, and skeletal muscle. SIRPG is an immunoglobulin-like cell surface receptor. On binding with CD47, SIRPG mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation. SIRPG as receptor-type transmembrane glycoproteins is involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes.