Recombinant Human SUMF1 (C-6His)

Description

EnkiLife provides the Recombinant Human SUMF1 (C-6His) protein,aslo know as Sulfatase-Modifying Factor 1,C-Alpha-Formylglycine-Generating Enzyme 1,SUMF1,FGE, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Sulfatase Modifying Factor 1 is produced by our Mammalian expression system and the target gene encoding Ser34-Asp374 is expressed with a 6His tag at the C-terminus.Accession:Q8NBK3. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:38.4 KDa. Background:Human Sulfatase Modifying Factor 1 (SUMF1) is a 42kDa protein. SUMF1 is a Ca2+-binging member of the sulfatase-modifying factor family. SUMF1 is a soluble ER lumenal glycoprotein, it converts inactive sulfatases into an active form by transforming a catalytic site cysteine into a formylglycine residue. In the ER, SUMF1 can exist as either a monomer, or a disulfide-linked homodimer or a heterodimer with SUMF2. Three splice isoforms are known.