Recombinant Human TAFA4 (N-6His)

Description

EnkiLife provides the Recombinant Human TAFA4 (N-6His) protein,aslo know as Protein FAM19A4;Chemokine-like protein TAFA-4;TAFA4;family with sequence similarity 19 (chemokine (C-C motif)-like),member A4,FAM19A4,chemokine-like protein TAFA-4, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Family with Sequence Similarity 19, Member A4 is produced by our E.coli expression system and the target gene encoding Ser35-Arg140 is expressed with a 6His tag at the N-terminus.Accession:Q96LR4. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:14.1 KDa. Background:FAM19A4 is a secreted, 12 kDa member of the FAM19/TAFA family of chemokine-like proteins. Like other members of the FAM19/TAFA family, with the exception of TAFA5, mature FAM19A4 contains 10 regularly spaced cysteine residues. The FAM19A4 proteins are predominantly expressed in specific regions of the brain and the biological functions of FAM19A4 family members remain to be determined, but there are a few tentative hypotheses. First, FAM19A4 may modulate immune responses in the CNS by functioning as brain specific chemokines, and may act with other chemokines to optimize the recruitment and activity of immune cells in the CNS. Second, FAM19A4 may represent a novel class of neurokines that act as regulators of immune nervous cells. And third, FAM19A4 may control axonal sprouting following brain injury.