Recombinant Human TCblR (C-6His)

Description

EnkiLife provides the Recombinant Human TCblR (C-6His) protein,aslo know as CD320 antigen;8D6 antigen;FDC-signaling molecule 8D6;FDC-SM-8D6;Transcobalamin receptor;TCblR;CD320, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Transcobalamin II Receptor is produced by our Mammalian expression system and the target gene encoding Ser36-Val231 is expressed with a 6His tag at the C-terminus.Accession:Q9NPF0. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:21.1 KDa. Background:CD320 antigen is also known as 8D6 antigen，FDC-signaling molecule 8D6，Transcobalamin receptor and 8D6A. It is a single-pass type I membrane protein and containing two LDL-receptor class A domains. CD320 has been recently discovered and reported as a follicular dendritic cell (FDC) protein. CD320 can augments the proliferation of plasma cells precursors generated by IL-10. CD320 also founctions a receptor for the cellular uptake of transcobalamin bound cobalamin. Defects in CD320 are the cause of methylmalonic aciduria type TCblR (MMATC) which is a metabolic disorder.