Recombinant Human TDT (N-6His)

Description

EnkiLife provides the Recombinant Human TDT (N-6His) protein,aslo know as DNA nucleotidylexotransferase,Terminal addition enzyme,Terminal deoxynucleotidyltr,Terminal deoxynucleotidyltransferase,Terminal transferase,DNTT,TDT, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human DNA Nucleotidylexotransferase is produced by our E.coli expression system and the target gene encoding Met1-Ala509 is expressed with a 6His tag at the N-terminus.Accession:P04053. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:60.7 KDa. Background:Terminal deoxynucleotidyl transferase (TdT) is a highly conserved vertebrate enzyme that possesses the unique ability to catalyze the random addition of deoxynucleoside 5-triphosphates onto the 3-hydroxyl group of a single-stranded DNA. It plays an important role in the generation of immunoglobin and T-cell receptor diversity. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.