Recombinant Human TPM3

Description

EnkiLife provides the Recombinant Human TPM3 protein,aslo know as Tropomyosin Alpha-3 Chain,Gamma-Tropomyosin,Tropomyosin-3,Tropomyosin-5,hTM5,TPM3, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Tropomyosin Alpha-3 Chain is produced by our E.coli expression system and the target gene encoding Met1-Met248 is expressed.Accession:P06753-2. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:29 KDa. Background:Tropomyosin Alpha-3 Chain (TPM3) is a member of the Tropomyosin family. TPM3 exists as a heterodimer consisting of an alpha and a beta chain. TPM3 plays a central role in association with the Troponin complex and in the calcium dependent regulation of vertebrate striated muscle contraction. Defects in TPM3 are the cause of thyroid papillary carcinoma. Mutations in the TPM3 gene cause autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are linked with cancer.