Recombinant Human TREM-1 (C-6His)

Description

EnkiLife provides the Recombinant Human TREM-1 (C-6His) protein,aslo know as Triggering Receptor Expressed on Myeloid Cells 1,TREM-1,Triggering Receptor Expressed on Monocytes 1,CD354,TREM1, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Triggering Receptor Expressed on Myeloid Cells 1 is produced by our Mammalian expression system and the target gene encoding Ala21-Arg200 is expressed with a 6His tag at the C-terminus.Accession:Q9NP99. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:21.3 KDa. Background:Triggering Receptor Expressed on Myeloid Cells 1 (TREM-1) is a transmembrane protein with a single Ig-like domain. TREM-1 associates with the adapter protein, DAP12, to deliver an activating signal. TREM-1 is expressed on blood neutrophils and monocytes, and the expression is up-regulated by bacterial LPS. TREM-1 is expressed at high levels on neutrophils of patients with microbial sepsis and in mice with a TREM-1/Fc fusion protein protected mice against LPS-induced shock. Human TREM-1 shares 42% sequence homology with mouse TREM-1.