Recombinant Human UBA5 (N-6His)

Description

EnkiLife provides the Recombinant Human UBA5 (N-6His) protein,aslo know as Ubiquitin-like modifier-activating enzyme 5,ThiFP1,UFM1-activating enzyme,Ubiquitin-activating enzyme E1 domain-containing protein 1,UBE1DC1,UBA5, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Ubiquitin-fold Modifier 1 Activating Enzyme is produced by our E.coli expression system and the target gene encoding Met1-Met404 is expressed with a 6His tag at the N-terminus.Accession:Q9GZZ9. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:47 KDa. Background:UBA5 is a member of the ubiquitin-activating E1 family and UBA5 subfamily. Ubiquitin and ubiquitin-like proteins are recognized as covalently conjugated to various cellular substrates by a three-step enzymatic pathway. The ubiquitin-activating enzyme (E1) has a vital role in the first step of ubiquitination pathway to activate ubiquitin or ubiquitin-like proteins. UBA5 activates ubiquitin-fold modifier 1, a ubiquitin-like post-translational modifier protein, via the formation of a high-energy thioester bond. UBA5 is located primarily in cytoplasm, while it generally localizes to the nucleus in presence of SUMO2.