Recombinant Human UBE2A (N-GST, 6His)

Description

EnkiLife provides the Recombinant Human UBE2A (N-GST, 6His) protein,aslo know as Ubiquitin-Conjugating Enzyme E2 A,RAD6 Homolog A,HR6A,hHR6A,Ubiquitin Carrier Protein A,Ubiquitin-Protein Ligase A,UBE2A,RAD6A, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Ubiquitin-Conjugating Enzyme E2 A is produced by our E.coli expression system and the target gene encoding Met1-Cys152 is expressed with a GST, 6His tag at the N-terminus.Accession:P49459. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:49 KDa. Background:Ubiquitin-Conjugating Enzyme E2 (UBE2A) is a member of the E2 Ubiquitin-Conjugating Enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2A catalyzes the covalent attachment of ubiquitin to other proteins. UBE2A is required for postreplication repair of UV-damaged DNA. UBE2A Interacts with RAD18 and WAC.