Recombinant Human UBE2S (N-GST)

Description

EnkiLife provides the Recombinant Human UBE2S (N-GST) protein,aslo know as Ubiquitin-Conjugating Enzyme E2 S,E2-EPF,Ubiquitin Carrier Protein S,Ubiquitin-Conjugating Enzyme E2-24 kDa,Ubiquitin-Conjugating Enzyme E2-EPF5,Ubiquitin-Protein Ligase S,UBE2S,E2EPF, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Ubiquitin-Conjugating Enzyme E2 S is produced by our E.coli expression system and the target gene encoding Met1-Leu222 is expressed with a GST tag at the N-terminus.Accession:Q16763. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:50.13 KDa. Background:Ubiquitin-Conjugating Enzyme E2 S (UBE2S) is a member of the Ubiquitin-Conjugating Enzyme family. UBE2S interacts with CDC20, FZR1/CDH1 and VHL. UBE2S can form a thiol ester linkage with Ubiquitin in an Ubiquitin Activating Enzyme-Dependent manner, a characteristic property of Ubiquitin Carrier Proteins. UBE2S acts as an essential factor of the Anaphase Promoting Complex/Cyclosome, a cell cycle-regulated Ubiquitin ligase that controls progression through mitosis. UBE2S is also involved in ubiquitination and subsequent degradation of VHL, resulting in an accumulation of HIF1A.