Recombinant Human UBE2V2 (N-6His)

Description

EnkiLife provides the Recombinant Human UBE2V2 (N-6His) protein,aslo know as Ubiquitin-Conjugating Enzyme E2 Variant 2,DDVit 1,Enterocyte Differentiation-Associated Factor 1,EDAF-1,Enterocyte Differentiation-Promoting Factor 1,EDPF-1,MMS2 Homolog,Vitamin D3-Inducible Protein,UBE2V2,MMS2,UEV2, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Ubiquitin-Conjugating Enzyme E2 Variant 2 is produced by our E.coli expression system and the target gene encoding Met1-Asn145 is expressed with a 6His tag at the N-terminus.Accession:Q15819. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:18.5 KDa. Background:Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2) is an enzyme that belongs to the ubiquitin-conjugating enzyme family. UBE2V2 can be detected in the placenta, colon, liver, and skin. It forms a heterodimer with UBE2N. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains and which leads to protein degradation by the proteasome. UBE2V2 mediates transcriptional activation of target genes. It plays a role in the control of progress through the cell cycle and differentiation. It also plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.