Recombinant Human UCH-L1 (C-6His)

Description

EnkiLife provides the Recombinant Human UCH-L1 (C-6His) protein,aslo know as Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L1,UCH-L1,Neuron Cytoplasmic Protein 9.5,PGP 9.5,PGP9.5,Ubiquitin Thioesterase L1,UCHL1, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L1 is produced by our E.coli expression system and the target gene encoding Met1-Ala223 is expressed with a 6His tag at the C-terminus.Accession:P09936. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:25.89 KDa. Background:Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L1 (UCHL1) belongs to the Peptidase C12 family. UCHL1 is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. UCHL1 is a component of the ubiquitin system, which has a fundamental role in regulating various biological activities. UCHL1 is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. UCHL1 also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer of UCHL1 may have ATP-independent ubiquitin ligase activity.