Recombinant Human UPK2 (C-6His)

Description

EnkiLife provides the Recombinant Human UPK2 (C-6His) protein,aslo know as Uroplakin-2,UP2,Uroplakin II,UPII,UPK2, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Uroplakin-2 is produced by our Mammalian expression system and the target gene encoding Asp26-Gly155 is expressed with a 6His tag at the C-terminus.Accession:O00526. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:14.84 KDa. Background:Uroplakin-2 is a single-pass type I membrane protein that belongs to the uroplakin-2 family. Uroplakin-2 is a component of the asymmetric unit membrane (AUM) and expressed in the ureter, a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. Uroplakin-2 forms heterodimer with UPK1A that is necessary for exiting out of the endoplasmic reticulum (ER). Uroplakin-2 may play an important role in regulating the assembly of the AUM. AUM is believed to strengthen the urothelium by preventing cell rupture during bladder distention.