Recombinant Human UPRT (N-6His)

Description

EnkiLife provides the Recombinant Human UPRT (N-6His) protein,aslo know as Uracil phosphoribosyltransferase homolog,UPP,FUR1,UPRT, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Uracil Phosphoribosyltransferase Homolog is produced by our E.coli expression system and the target gene encoding Met1-Asp309 is expressed with a 6His tag at the N-terminus.Accession:Q96BW1. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:35.9 KDa. Background:UPRT is a cytoplasmic enzyme which belongs to the UPRTase family. UPRT is highly expressed in leukocytes, liver, spleen and thymus, with lower expression in brain, lung and skeletal muscle. UPRTcatalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. UPRT is a potential target for rational design of drugs to treat parasitic infections and cancer