Recombinant Human UROIIIS (C-6His)

Description

EnkiLife provides the Recombinant Human UROIIIS (C-6His) protein,aslo know as Uroporphyrinogen-III Synthase,UROIIIS,UROS,Hydroxymethylbilane Hydrolyase [Cyclizing],Uroporphyrinogen-III Cosynthase,UROS, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Uroporphyrinogen-III Synthase is produced by our E.coli expression system and the target gene encoding Met1-Cys265 is expressed with a 6His tag at the C-terminus.Accession:P10746. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:29.7 KDa. Background:Uroporphyrinogen-III Synthase is an enzyme which belongs to the uroporphyrinogen-III synthase family. Uroporphyrinogen-III Synthase is ubiquitous and it is involved in Porphyrin metabolism. Porphyrins act as cofactors for a multitude of enzymes that perform a variety of processes within the cell such as Methionine synthesis (Vitamin B12) or oxygen transport (Heme). Uroporphyrinogen-III Synthase can catalyze cyclization of the linear Tetrapyrrole, Hydroxymethylbilane, to the Macrocyclic Uroporphyrinogen III, the branch point for the various sub-pathways leading to the wide diversity of Porphyrins. Defects in Uroporphyrinogen-III Synthase are the cause of Congenital Erythropoietic Porphyria (CEP).