Recombinant Human Vitronectin

Description

EnkiLife provides the Recombinant Human Vitronectin protein,aslo know as Vitronectin, VN, S-Protein, Serum-Spreading Factor, V75, VTN, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:≤1 EU/mg;Construction:Recombinant Human Vitronectin is produced by our Mammalian cell expression system and the target gene encoding Asp20-Leu478 is expressed.Accession:P04004. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:52.3 kDa. Background:Vitronectin is also known as S-protein, VN, VTN, V75. Vitronectin, a multifunctional glycoprotein, is involved in coagulation, inhibition of the formation of the membrane attack complex (MAC), cell adhesion and migration, wound healing, and tissue remodeling. The primary cellular source of vitronectin is hepatocytes. Blocking of Hic(a member of the pneumococcal surface protein C (PspC) family) by specific antiserum or genetic deletion significantly reduced pneumococcal binding to soluble and immobilised vitronectin and to Factor H, respectively. In addition, Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway.