Recombinant Human Vitronectin

Description

EnkiLife provides the Recombinant Human Vitronectin protein,aslo know as Vitronectin,VTN,VN,V75,Serum-spreading factor, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<0.01 EU/µg as determined by LAL test.;Construction:Recombinant Human Vitronectin is produced by our E.coli expression system and the target gene encoding Val62-Leu478 is expressed.Accession:AAH05046.1. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:47.6 KDa. Background:Vitronectin is a multifunctional glycoprotein present in blood and in the extracellular matrix. It binds glycosaminoglycans, collagen, plasminogen and the urokinase-receptor, and also stabilizes the inhibitory conformation of plasminogen activation inhibitor-1. Vitronectin may play an important role in wound healing and in tumorprogression. Vitronectin deposition has been detected in areas of brosis and necrosis in a variety of diseases, including membranous nephropathy, arteriosclerosis and degenerative central nervous system disorders.