Recombinant Human VSTM1 (C-6His)

Description

EnkiLife provides the Recombinant Human VSTM1 (C-6His) protein,aslo know as V-set and transmembrane domain-containing protein 1;SIRL-1;Signal inhibitory receptor on leukocytes-1;VSTM1, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human V-set And Transmembrane Domain-Containing Protein 1 is produced by our Mammalian expression system and the target gene encoding Tyr17-Thr135 is expressed with a 6His tag at the C-terminus.Accession:Q6UX27. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:14.6 KDa. Background:V-set and transmembrane domain-containing protein 1 is a single-pass membrane protein. VSTM1 Contains 1 Ig-like V-type domain, in humans is encoded by the VSTM1 gene. It expressed on myeloid (neutrophils, eosinophils and monocytes) but not on lymphoid cells. It behaves as a cytokine, promoting IL17A secretion by CD4+ T-cells, and differentiation and activation of IL17 producing helper T-cells (TH17). Inhibitory immune receptor involved in the regulation of phagocytes.