Recombinant Human WARS (N-6His)

Description

EnkiLife provides the Recombinant Human WARS (N-6His) protein,aslo know as WARS also known as Tryptophanyl-tRNA synthetase,Interferon-induced protein 53, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Tryptophan-tRNA ligase, Cytoplasmic is produced by our E.coli expression system and the target gene encoding Met1-Gln471 is expressed with a 6His tag at the N-terminus.Accession:P23381. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:55.3 KDa. Background:There exists two types of tryptophanyl tRNA synthetases, the cytoplasmic form called WARS, the mitochondrial form called WARS2. WARS catalyzes the aminoacylation of tRNA (trp) with tryptophan and is induced by interferon. WARS regulates ERK, Akt, eNOS activation pathway, which are related with angiogenesis, cytoskelatal reorganization and shear stess-reponsive gene expression.