Recombinant Human XPNPEP2 (C-6His)

Description

EnkiLife provides the Recombinant Human XPNPEP2 (C-6His) protein,aslo know as Xaa-Pro Aminopeptidase 2,Aminoacylproline Aminopeptidase,Membrane-Bound Aminopeptidase P,Membrane-Bound APP,Membrane-Bound AmP,mAmP,X-Pro Aminopeptidase 2,XPNPEP2, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Xaa-Pro Aminopeptidase 2 is produced by our Mammalian expression system and the target gene encoding His22-Ala650 is expressed with a 6His tag at the C-terminus.Accession:O43895. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:71.64 KDa. Background:Xaa-Pro aminopeptidase 2 (XPNPEP2) belongs to the peptidase M24B family of metalloproteases. Human XPNPEP2 is widely expressed in various tissues, such as kidney, lung, heart, placenta, liver, small intestine and colon. However, it doesn’t express in brain, skeletal muscle, pancreas, spleen, thymus, prostate, testis and ovary. XPNPEP2 is a Homotrimer which binds 2 manganese ions per subunit. The metalloprotease XPNPEP2 may play a role in the inflammatory process and other reactions produced in response to injury or infection and the metabolism of the vasodilator bradykinin.