Recombinant Macaca nemestrina PCSK9 (C-6His)

Description

EnkiLife provides the Recombinant Macaca nemestrina PCSK9 (C-6His) protein,aslo know as Proprotein Convertase Subtilisin/Kexin Type 9,Proprotein Convertase 9,PC9,Subtilisin/Kexin-Like Protease PC9,PCSK9, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Macaca Nemestrina Proprotein Convertase Subtilisin/Kexin Type 9/PCSK9 is produced by our Mammalian expression system and the target gene encoding Gln31-Gln152&Ser153-Gln692 is expressed with a 6His tag at the C-terminus.Accession:A8T662. Expression Host:Human Cells.Species:Macaca nemestrina.Predicted Molecular Mass:1459 KDa. Background:Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. PCSK9 also plays a role in the neural development.