Recombinant Mouse BTNL6 (C-6His)

Description

EnkiLife provides the Recombinant Mouse BTNL6 (C-6His) protein,aslo know as BTNL6,Gm6519,NG13,Butyrophilin-like 6,EG624681, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Mouse Butyrophilin-like 6 is produced by our Mammalian expression system and the target gene encoding Lys29-Trp249 is expressed with a 6His tag at the C-terminus.Accession:A2CG22. Expression Host:Human Cells.Species:Mouse.Predicted Molecular Mass:25.6 KDa. Background:Butyrophilin-like 6 (BTNL6) is a member of the BTN/MOG Ig-superfamily and functions with BTNL1 as a regulator of immune cell proliferation. The Btnl6 gene is found only in mice. BTNL6 expression is coordinated as a heteromeric protein with BTNL1, and the presence of this complex is correlated with expansion of gamma δ T cells, especially those containing V gamma 7Vδ4 TCR. Btnl6 shows striking sequence similarity to Skint1; is also largely restricted to an epithelial tissue (the small intestine) replete with T cells. Our in-house studies showed BTNL6 co-inhibited anti-CD3 induced IL-2 secretion on CD3+ cells.