Recombinant Mouse Carbonic Anhydrase 14 (N-6His)

Description

EnkiLife provides the Recombinant Mouse Carbonic Anhydrase 14 (N-6His) protein,aslo know as Carbonic Anhydrase 14,Carbonate Dehydratase XIV,Carbonic Anhydrase XIV,CA-XIV,CA14, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Mouse Carbonic Anhydrase 14 is produced by our E.coli expression system and the target gene encoding Ala16-Met290 is expressed with a 6His tag at the N-terminus.Accession:Q9WVT6. Expression Host:E.coli.Species:Mouse.Predicted Molecular Mass:32.3 KDa. Background:Mouse Ca14,also known as Carbonic anhydrase 14,is a member of large family of zinc metalloenzymes .It could catalyze reversible hydration of carbon dioxide. The reaction is fundamental to many processes such as respiration, renal tubular acidification and bone resorption. Fifteen CA isoforms have been reported so far. They have different patterns of tissue-specific expression and physiologic roles. Some CAs may serve as markers for tumors and hypoxia. CA XIV is a polypeptide consisting of an extracellular N-terminal catalytic domain, a membrane-spanning segment and a short intracellular C- terminal segment with several potential phosphorylation sites. A subset of CAs lack CA activity due to point mutations but retain esterase function. CA14 is widely expressed in the central nervous system