Recombinant Mouse Carbonic Anhydrase 4 (C-6His)

Description

EnkiLife provides the Recombinant Mouse Carbonic Anhydrase 4 (C-6His) protein,aslo know as CA4,CAIV,CA-IV,Car4,Carbonate dehydratase IV,carbonic anhydrase 4,carbonic anhydrase IVRP17,carbonic dehydratase IV,EC4.2.1.1,retinitis pigmentosa 17,RP17, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Mouse Carbonic Anhydrase 4 is produced by our Mammalian expression system and the target gene encoding Glu18-Ser277 is expressed with a 6His tag at the C-terminus.Accession:Q64444. Expression Host:Human Cells.Species:Mouse.Predicted Molecular Mass:30.5 KDa. Background:Carbonic anhydrase 4(CA4) is an enzyme that belongs to the alpha-carbonic anhydrase family. CA4 consists of a signal peptide (residues1-17), an ectodomain (residues18-277) and a propeptide (residues278-305), which is removed in the mature form. it is predominantly expressed in the embryo. CA4 can catalyzes the reversible reaction of CO2+H2O=HCO3-+H+, and stimulates the sodium/bicarbonate transporter activity of SLC4A4. Studies have shown that this protein have a role in inherited renal abnormalities of bicarbonate transport. Alpha-carbonic anhydrase family participate in avariety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor. They show extensive diversity in tissue is attribution and in their sub cellular localization.