Recombinant Mouse CD27 (C-Fc-6His)

Description

EnkiLife provides the Recombinant Mouse CD27 (C-Fc-6His) protein,aslo know as CD27 antigen,CD27L receptor,T-cell activation antigen CD27,Tumor necrosis factor receptor superfamily member 7,CD27, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Mouse CD27 Antigen is produced by our Mammalian expression system and the target gene encoding Pro24-Arg182 is expressed with a human IgG1 Fc, 6His tag at the C-terminus.Accession:P41272. Expression Host:Human Cells.Species:Mouse.Predicted Molecular Mass:45.8 KDa. Background:Mouse CD27 is a single-pass type I membrane protein which is a member of the tumor necrosis factor receptor superfamily. CD27 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. CD27 transduces signals that lead to the activation of NF-κB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.