Recombinant Mouse CD39 (C-6His)

Description

EnkiLife provides the Recombinant Mouse CD39 (C-6His) protein,aslo know as Ectonucleoside triphosphate diphosphohydrolase 1,NTPDase 1,NTPDase 1,Ecto-ATP diphosphohydrolase 1,Ecto-ATPDase 1,Ecto-ATPase 1,Ecto-apyrase,Lymphoid cell activation antigen,CD39, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Mouse Ectonucleoside Triphosphate Diphosphohydrolase 1 is produced by our Mammalian expression system and the target gene encoding Thr38-Ile478 is expressed with a 6His tag at the C-terminus.Accession:P55772. Expression Host:Human Cells.Species:Mouse.Predicted Molecular Mass:50.5 KDa. Background:Ectonucleoside triphosphate diphosphohydrolase-1(NTPDase-1) is an integral membrane protein with an extracellular active site. NTPDase-1 was originally described as CD39, a B lymphocyte cell surface marker. But it is also present on the surface of natural killer cells, T cells, and some endothelial cells. NTPDase1 hydrolyzes the β-andγ phosphate residues of nucleotides, preferring ATP as the substrate. Through its hydrolysis of extracellular nucleotides, NTPDase-1 plays a role in the regulation of purinergic signaling. NTPDase-1 is involved in the processes of thromboregulation and vascular inflammation. The administration of soluble NTPDase-1 may have therapeutic applications for the treatment of some vascular and transplantation-associated diseases.