Recombinant Mouse CES3 (C-6His)

Description

EnkiLife provides the Recombinant Mouse CES3 (C-6His) protein,aslo know as CES3,carboxylesterase 3,carboxylesterase 3 (brain),EC 3.1.1,EC 3.1.1.1,ES31FLJ21736,Esterase 31,Liver carboxylesterase 31 homolog, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Mouse Carboxylesterase 3 is produced by our Mammalian expression system and the target gene encoding Tyr19-Glu561 is expressed with a 6His tag at the C-terminus.Accession:Q8VCT4. Expression Host:Human Cells.Species:Mouse.Predicted Molecular Mass:62.4 KDa. Background:Mouse Carboxylesterases 3 (CES3) is a member of five families of mammalian carboxylesterases that plays a role in catalyzing hydrolytic and transesterification reactions with xenobiotics, anticancer pro-drugs and narcotics, and detoxifying organophosphates and insecticides. Mammalian carboxylesterases are enzymes with broad substrate specificities ranging from small molecule esters to longchain fatty acid esters. It is shown that CESs has key roles in the metabolism of a wide variety of clinical drugs, illicit narcotics and chemical nerve agents. CES3 is broadly expressed in liver, colon and brain.