Recombinant Mouse CHI3L3 (C-6His)

Description

EnkiLife provides the Recombinant Mouse CHI3L3 (C-6His) protein,aslo know as Chitinase-like protein 3,Chil3, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Mouse Chitinase-Like Protein 3 is produced by our Mammalian expression system and the target gene encoding Tyr22-Tyr398 is expressed with a 6His tag at the C-terminus.Accession:O35744. Expression Host:Human Cells.Species:Mouse.Predicted Molecular Mass:43.4 KDa. Background:Chitinase 3-like 3 gene, also known as YM1 and ECF-L, encodes a precursor protein with 398 amino acid residues with a 21 residue signal sequence. Chitinase 3-like 3 protein is a lectin that binds saccharides with a free amino group, such as glucosamine or galactosamine. Binding to oligomeric saccharides is much stronger than binding to mono- or disaccharides. Also binds heparin and G1cN oligomers, and is produced primarily by macrophages during inflammation. It has chemotactic activity for T-lymphocytes, bone marrow cells and eosinophils.