Recombinant Mouse CXCL9 (C-6His)

Description

EnkiLife provides the Recombinant Mouse CXCL9 (C-6His) protein,aslo know as C-X-C motif chemokine 9,Gamma-interferon-induced monokine,Monokine induced by interferon-gamma,MIG,MuMIG,Protein m119,Small-inducible cytokine B9,Cxcl9,Mig,Scyb9, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Mouse C-X-C Motif Chemokine 9 is produced by our Mammalian expression system and the target gene encoding Thr22-Thr126 is expressed with a 6His tag at the C-terminus.Accession:P18340. Expression Host:Human Cells.Species:Mouse.Predicted Molecular Mass:13 KDa. Background:Chemokine (C-X-C motif) ligand 9 (CXCL9, MIG), is a small cytokine belonging to the CXC chemokine family. CXCL9 functions as one of the three ligands of chemokine receptor CXCR3 which is a G protein-coupled receptor found predominantly on T cells. It together with CXCL10 and CXCL11, may activate CXCR3 by binding to it. CXCL9 serves as a cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. It has been observed that tumour endothelial cells secrete high levels of CXCL9 in all, and CXCL10 in most melanoma metastases. it plays an important role in CD4+ T lymphocyte recruitment and development of CAV, MOMA-2+ macrophages are the predominant recipient-derived source of CXCL9, and recipient CD4 lymphocytes are necessary for sustained CXCL9 production and CAV development in this model.