Recombinant Mouse Cystatin B (N-6His)

Description

EnkiLife provides the Recombinant Mouse Cystatin B (N-6His) protein,aslo know as CPI-B,CST6cystatin B (liver thiol proteinase inhibitor)10STFBcystatin-B,CSTB,cystatin B (stefin B),Cystatin B,EPM1,Liver thiol proteinase inhibitor,PME,Stefin B,stefin-B, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Mouse Cystatin-B is produced by our E.coli expression system and the target gene encoding Met1-Phe98 is expressed with a 6His tag at the N-terminus.Accession:Q62426. Expression Host:E.coli.Species:Mouse.Predicted Molecular Mass:13.3 KDa. Background:Cystatin B, also called stefin B or liver thiol proteinase inhibitor, is a member of family 1 of the cystatin superfamily. Like Cystatin A, it is an intracellular inhibitor regulating the activities of cysteine proteases of the papain family such as cathepsins B, H and L. Defects in Cystatin-B / CSTB are the cause of progressive myoclonic epilepsy type 1 (EPM1) which is an autosomal recessive disorder characterized by severe, stimulus-sensitive myoclonus and tonic-clonic seizures.