Recombinant Mouse Fetuin A (C-10His)

Description

EnkiLife provides the Recombinant Mouse Fetuin A (C-10His) protein,aslo know as Alpha-2-HS-glycoprotein,Ahsg,Countertrypin,Fetuin-A,Fetua, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Mouse Alpha-2-HS-Glycoprotein is produced by our Mammalian expression system and the target gene encoding Ala19-Ile345 is expressed with a 10His tag at the C-terminus.Accession:P29699. Expression Host:Human Cells.Species:Mouse.Predicted Molecular Mass:36.7 KDa. Background:Alpha-2-HS-glycoprotein (AHSG) is a glycoprotein that is composed of two subunits, the A and B chains, belongs to the Cystatin family of proteases inhibitors. It is highly expressed in embryonic cells and adult hepatocytes, and is expressed to a lesser extent in monocytes/macrophages. AHSG is an important circulating inhibitor of calcification in vivo, and is downregulated during the acute-phase response. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. In addition, AHSG may influence the resolution of inflammation by modulating the phagocytosis of apoptotic cells by macrophages. ASHG blocks TGF-beta-dependent signaling in osteoblastic cells.