Recombinant Mouse HGF (C-6His)

Description

EnkiLife provides the Recombinant Mouse HGF (C-6His) protein,aslo know as Hepatopoietin-A,Scatter factor,SF,deafness,autosomal recessive 39,DFNB39,F-TCF,hepatocyte growth factor, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<0.01 EU/µg as determined by LAL test.;Construction:Recombinant Mouse Hepatocyte Growth Factor is produced by our Mammalian expression system and the target gene encoding Gln33-/xadLeu728 is expressed with a 6His tag at the C-terminus.Accession:Q08048. Expression Host:Human Cells.Species:Mouse.Predicted Molecular Mass:53.5&26.9 KDa. Background:HGF, is a pleiotropic protein in the Plasminogen subfamily of S1 peptidases. Mouse HGF is secreted as an inactive 728 amino acid (aa) single chain propeptide. It is cleaved after the fourth Kringle domain by a serine protease to form bioactive disulfide-linked HGF with a 60/xa0kDa alpha /xa0and 30 kDa beta /xa0chain. HGF binds heparan-sulfate proteoglycans and the widely expressed receptor tyrosine kinase, HGF R/c-MET. HGF regulates epithelial morphogenesis by inducing cell scattering and branching tubulogenesis. /xa0It can also alter epithelium morphology by the induction of nectin‑1 alpha /xa0ectodomain shedding, an adhesion protein component of adherens junctions/xa0.