Recombinant Mouse IL-2

Description

EnkiLife provides the Recombinant Mouse IL-2 protein,aslo know as aldesleukin,interleukin 2,interleukin-2,IL-2,IL2,T-cell growth facter,T cell growth factor,TCGF, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<0.01 EU/µg as determined by LAL test.;Construction:Recombinant Mouse Interleukin-2 is produced by our E.coli expression system and the target gene encoding Ala21-Gln169 is expressed.Accession:P04351. Expression Host:E.coli.Species:Mouse.Predicted Molecular Mass:17.4 KDa. Background:Interleukin 2 (IL 2), also termed T-cell growth factor, is a member of the cytokine family which includes IL-4, IL-7, IL-9, IL-15 and IL-21. Each member of this family has a four alpha helix bundle. IL-2 signals through the IL-2 receptor, a complex consisting of tree subunits, termed alpha, beta and gamma. The IL-2 R gamma is shared by cytokine receptors of all members of cytokine family. Mature mouse IL/xad2 shares 56% and 73% aa sequence identity with human and rat IL/xad2, respectively. IL-2 is produced by CD4+ T cell, CD8+ T cells, gamma δ T cells, B cells, dendritic cells and eosinophils, and plays a vital role in key function of the immune system, tolerance and immunity, primarily via its potent stimulatory activity for T cells.Thus, IL/xad2 may be a key cytokine in the natural suppression of autoimmunity.