Recombinant Mouse IL-36 gamma

Description

EnkiLife provides the Recombinant Mouse IL-36 gamma protein,aslo know as Interleukin-36 gamma,IL36G,IL-1-related protein 2,IL-1RP2,IL-1 epsilon,IL-1F9,Interleukin-1 homolog 1,IL-1H1, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Mouse Interleukin-36 Gamma is produced by our E.coli expression system and the target gene encoding Gly13-Ser164 is expressed.Accession:Q8R460. Expression Host:E.coli.Species:Mouse .Predicted Molecular Mass:17.3 KDa. Background:Interleukin-36 gamma (IL-36γ) is a member of the interleukin 1 cytokine family that includes three closely related genes, IL-36α, β, and γ, formerly known as IL-1F6, F8, and F9 respectively. IL-36α has been detected in both neuronal and synovial tissue, whereas IL-36β and IL-36γ are expressed in both cutaneous and mucosal epithelial cells, including the respiratory tract. IL-36β and IL-36γ stimulate proliferation, maturation and/or cytokine expression by innate immune cells (such as keratinocytes and dendritic cells), and adaptive immune cells (neutrophils and T-cells) in both humans and mice. The activity of IL-36α is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). IL-36γ plays an important role in communicating the cell death to surrounding cells.