Recombinant Mouse IMPA3 (N-6His)

Description

EnkiLife provides the Recombinant Mouse IMPA3 (N-6His) protein,aslo know as Inositol monophosphatase 3,Impad1, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Mouse Inositol Monophosphatase 3 is produced by our Mammalian expression system and the target gene encoding Glu51-His356 is expressed with a 6His tag at the N-terminus.Accession:Q80V26. Expression Host:Human Cells.Species:Mouse.Predicted Molecular Mass:34.3 KDa. Background:IMPAD1 protein (IMPA3, gPAPP or IMPase 3) belongs to the inositol monophosphatase family. It is found in Purkinje cells, brain stem, lung and chondrocytes. Mouse IMPAD1 gene encodes a type II transmembrane Golgi-embedded glycoprotein with 356 amino acid residues which generates a 306 amino acid residues mature protein after processing. It is expressed in embryo, and in theory may catalyze myo-inositol monophosphate to myo-inositol. Free myo-inositol is used to generate inositol phospholipid, an essential component of intracellular signaling pathways that mobilize calcium. Mouse IMPAD1 exhibits 91% sequence identity with the human homologue.