Recombinant Mouse MMP-12 (C-6His)

Description

EnkiLife provides the Recombinant Mouse MMP-12 (C-6His) protein,aslo know as Macrophage metalloelastase,MME,Matrix metalloproteinase-12,MMP-12,Mmp12,Mme,Mmel, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Mouse Matrix Metalloproteinase 12 is produced by our Mammalian expression system and the target gene encoding Ala29-Cys473 is expressed with a 6His tag at the C-terminus.The proenzyme needs to be activated by APMA for an activated form.Accession:P34960. Expression Host:Human Cells.Species:Mouse.Predicted Molecular Mass:53 KDa. Background:Matrix metalloproteinase-12（MMP12） is a secreted protein.It contains 4 hemopexin repeats and belongs to the peptidase M10A family. MMP12 may be involved in tissue injury and remodeling and have significant elastolytic activity. It can accept large and small amino acids at the P1 site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.