Recombinant Mouse Nectin-2 (C-6His)

Description

EnkiLife provides the Recombinant Mouse Nectin-2 (C-6His) protein,aslo know as CD112,nectin2,Herpes virus entry mediator B,Herpesvirus entry mediator B,HveB;Murine herpes virus entry protein B,mHveB;Poliovirus receptor homolog,Poliovirus receptor-related protein 2,Pvrl2, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Mouse Poliovirus Receptor-Related Protein 2 is produced by our Mammalian expression system and the target gene encoding Gln32-Gly351 is expressed with a 6His tag at the C-terminus.Accession:P32507. Expression Host:Human Cells.Species:Mouse.Predicted Molecular Mass:35.6 KDa. Background:Nectin-2( CD112) is a member of the nectin family, which contains two Ig-like C2-type domains and one Ig-like V-type domain in the extracellular region. Nectins are type I transmembrane glycoproteins that are calcium-independent immunoglobulin (Ig)-like cell adhesion molecules (CAMs). Nectin2 is widely expressed in human tissues including brain, spinal cord, spleen, kidney, heart and liver. It can form trans-heterodimers with PVRL3/nectin-3 and interacts with CD226. Mutations of alleles of the murine CD112 gene can result in conditions such as morphologically aberrant spermatozoa. It may function in allergic reactions, and accordingly may used as a novel target for anti-allergic therapy.