Recombinant Mouse PSMA (N-6His)

Description

EnkiLife provides the Recombinant Mouse PSMA (N-6His) protein,aslo know as Glutamate carboxypeptidase 2,FGCP,GCPII,mGCP,NAALADase I,PSMA,Cell growth-inhibiting gene 27 protein,Folate hydrolase 1, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Mouse Glutamate carboxypeptidase 2 is produced by our Mammalian expression system and the target gene encoding Ile44-Ala752 is expressed with a 6His tag at the N-terminus.Accession:Q0VDM5. Expression Host:Human Cells.Species:Mouse.Predicted Molecular Mass:80.7 KDa. Background:Glutamate carboxypeptidase 2, also known as FOLH1, PSMA, belongs to the M28B subfamily and the peptidase M28 family. It is highly expressed in prostate epithelium and can be detected in urinary bladder, kidney, testis, ovary, fallopian tube, breast, adrenal gland, liver, esophagus, stomach, small intestine, colon and brain (at protein level). PSMA is used as a diagnostic and prognostic indicator of prostate cancer, and as a possible marker for various neurological disorders such as schizophrenia, Alzheimer disease and Huntington disease. It has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity and has a preference for tri-alpha-glutamate peptides. PSMA involves in prostate tumor progression and also exhibits a dipeptidyl-peptidase IV type activity. In vitro, PSMA cleaves Gly-Pro-AMC. PSMA is stable at pH greater than 6.5.