Recombinant Mouse SECTM1A (C-6His)

Description

EnkiLife provides the Recombinant Mouse SECTM1A (C-6His) protein,aslo know as SECTM1A,Sectm1a, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Mouse Secreted And Transmembrane Protein 1A is produced by our Mammalian expression system and the target gene encoding Gln28/xadThr165 is expressed with a 6His tag at the C-terminus.Accession:A2ABP9. Expression Host:Human Cells.Species:Mouse.Predicted Molecular Mass:16.2 KDa. Background:SECTM1A (secreted and transmembrane 1A), is 192 amino acid (aa) protein, appears to share structural and functional characteristics with other SECTM1 proteins. Human SECTM1 can be found either found as an approximately 27 kDa intracellular type I transmembrane protein that shows a perinuclear, Golgi like staining pattern, or as a 20 kDa soluble, secreted form, and is produced by some myeloid cells and by thymic epithelia and fibroblasts. Stimulation with IFN gamma is often necessary to detect human SECTM1 expression, and it is thought to be an interferon early response gene. Mouse SECTM1A cDNA encodes a signal sequence, an extracellular domain with four potential N linked glycosylation sites, a transmembrane sequence, and a very short (approximately 6 aa) cytoplasmic sequence. SECTM1 proteins from human and mouse show species specific binding of CD7 and co stimulation of T cells, including enhancement of CD3 induced proliferation.