Recombinant Mouse Serpin F2 (C-6His)

Description

EnkiLife provides the Recombinant Mouse Serpin F2 (C-6His) protein,aslo know as Alpha-2-antiplasmin,Alpha-2-AP,Alpha-2-plasmin inhibitor,Alpha-2-PI,Serpin F2,Serpinf2, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Mouse Serine Protease Inhibitor-clade F2 is produced by our Mammalian expression system and the target gene encoding Val28-Lys491 is expressed with a 6His tag at the C-terminus.Accession:Q61247. Expression Host:Human Cells.Species:Mouse .Predicted Molecular Mass:53.2 KDa. Background:Alpha-2-antiplasmin, also called Serpin F2, is a serine protease inhibitor (serpin) responsible for inactivating plasmin, and an important enzyme participates in fibrinolysis and degradation of other proteins. In liver cirrhosis, there is decreased production of alpha 2-antiplasmin, leading to decreased inactivation of plasmin and an increase in fibrinolysis. Serpin F2 is major expressed on liver and kidney. Some other tissues such as muscle, intestine, central nervous system, and placenta also express Serpin F2 mRNA at a moderate level indicated that it is a key regulator of plasmin-mediated proteolysis in these tissues.