Recombinant Mouse TrkB (C-6His)

Description

EnkiLife provides the Recombinant Mouse TrkB (C-6His) protein,aslo know as BDNF/NT-3 Growth Factors Receptor,GP145-TrkB,Trk-B,Neurotrophic Tyrosine Kinase Receptor Type 2,TrkB Tyrosine Kinase,Tropomyosin-Related Kinase B,NTRK2,TRKB, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Mouse Neurotrophic Tyrosine Kinase Receptor Type 2 is produced by our Mammalian expression system and the target gene encoding Cys32-His429 is expressed with a 6His tag at the C-terminus.Accession:P15209. Expression Host:Human Cells.Species:Mouse.Predicted Molecular Mass:45.3 KDa. Background:The TRK Family of Tyrosine Kinase Receptor consists of 3 members: TrkA, TrkB and TrkC. The three TRK family proteins have different ligand specificities. They connect to different neurotrophins, including NGF, BDNF, NT-3NT-4/5. TRKA binds NGF, TRKB binds BDNF and NT-3, TRKC binds NT-4/5. At the protein sequence level, human and rat TRKB have greater than 90% sequence identity and the proteins exbihit cross-species activity. TRKB is primarily expressed in the nervous system and it also expression in a wide variety of tissues with low levels.