Recombinant Mouse TROP-2 (C-6His)

Description

EnkiLife provides the Recombinant Mouse TROP-2 (C-6His) protein,aslo know as Tumor-associated calcium signal transducer 2,Tacstd2,Trop2,Cell surface glycoprotein Trop-2, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Mouse Tumor-associated Calcium Signal Transducer 2 is produced by our Mammalian expression system and the target gene encoding Gln25-Gly270 is expressed with a 6His tag at the C-terminus.Accession:Q8BGV3. Expression Host:Human Cells.Species:Mouse.Predicted Molecular Mass:28.8 KDa. Background:Tumor-associated calcium signal transducer 2(Tacstd2), also known as Cell surface glycoprotein Trop-2, belongs to the EPCAM family. Tacstd2 expressed in kidney, lung, ovary and testis and has high levels of expression in immortalized keratinocytes. Tacstd2 may functions as a growth factor receptor. It has negative regulation of branching involved in ureteric bud morphogenesis, cell motility, epithelial cell migration, ruffle assembly, stress fiber assembly and substrate adhesion-dependent cell spreading. Also, it has positive regulation of stem cell proliferation. Tacstd2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions.