Recombinant Mouse VCAM-1 (C-Fc)

Description

EnkiLife provides the Recombinant Mouse VCAM-1 (C-Fc) protein,aslo know as Vascular cell adhesion protein 1,Vcam1, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Mouse Vascular Cell Adhesion Molecule 1 is produced by our Mammalian expression system and the target gene encoding Phe25-Glu698 is expressed with a human IgG1 Fc tag at the C-terminus.Accession:P29533. Expression Host:Human Cells.Species:Mouse.Predicted Molecular Mass:101.4 KDa. Background:Vascular cell adhesion molecule 1 (VCAM-1) is a cell surface protein belonging to the immunoglobulin superfamily, the protein is expressed by activated endothelial cells and certain leukocytes (such as macrophages). IL-1 beta, IL-4, TNF-alpha and IFN-gamma induced the expression of VCAM-1. The human and mouse VCAM-1 proteins share approximately 76% amino acid similarity. Mouse VCAM-1 is Important in cell-cell recognition. it appears to function in leukocyte-endothelial cell adhesion, and interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction.