Recombinant Rat CD73 (C-6His)

Description

EnkiLife provides the Recombinant Rat CD73 (C-6His) protein,aslo know as CD73,E5NT,Nucleotidase,NT5E,ecto-5-nucleotidase, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Rat 5-Nucleotidase/CD73 is produced by our Mammalian expression system and the target gene encoding Trp29-Lys549 is expressed with a 6His tag at the C-terminus.Accession:P21588. Expression Host:Human Cells.Species:Rat.Predicted Molecular Mass:59 KDa. Background:CD73, also known as Ecto-5-nucleotidase, is an ectoenzyme that is attached to the cell membrane by a glycosyl phophatidylinositol anchor. The enzyme is expressed by most cell types. The 5’-Nucleotidase activity of CD73 converts extracellular nucleoside-5’-monophosphates to nucleosides. CD73 is one of several enzymes responsible for the production of extracellular adenosine, a signaling molecule that is involved in responses to inflammation and tissue injury. CD73 hydrolyzes extracellular nucleotides into membrane permeable nucleosides.